Important studies presented at ESOC 2020
- Erik Lundström: EFFICACY OF FLUOXETINE – A RANDOMIZED CONTROLLED TRIAL IN STROKE (EFFECTS) Safety and efficacy of fluoxetine on functional recovery after acute stroke (EFFECTS): a randomised, double-blind, placebo-controlled trial – ScienceDirect
- Graeme Hankey: ASSESSMENT OF FLUOXETINE IN STROKE RECOVERY (AFFINITY): RESULTS OF A DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMISED TRIAL Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial – ScienceDirect
- Claiborne Johnson: TIGAGRELOR AND ASPIRIN VERSUS ASPIRIN ALONE IN ACUTE ISCHEMIC STROKE AND TIA: RESULTS OF THE THALES TRIAL Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA | NEJM
- Jianmin Liu: A RANDOMIZED TRIAL OF DIRECT ENDOVASCULAR THROMBECTOMY VERSUS THROMBECTOMY PRECEDED BY INTRAVENOUS ALTEPLASE IN ACUTE ISCHEMIC STROKE Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke | NEJM
- Wouter Schonewille: THE BASILAR ARTERY INTERNATIONAL COLLABORATION STUDY (BASICS): A RANDOMIZED CONTROLLED TRIAL OF ENDOVASCULAR THERAPY IN BASILAR ARTERY OCCLUSION Endovascular Therapy for Stroke Due to Basilar-Artery Occlusion | NEJM
- William Whiteley: ASCOT TRIAL: THE EFFECT OF RANDOMISATION TO ATORVASTATIN OR PLACEBO, AND AMLODOPINE-BASED OR BETA-BLOCKER-BASED REGIME ON 20-YEAR INCIDENCE OF STROKE OR DEMENTIA Long-Term Incidence of Stroke and Dementia in ASCOT | Stroke (ahajournals.org)
- Sara Mazzucco: DETERMINANTS OF PROGNOSIS OF CRYPTOGENIC STROKE IN PATIENTS WITH PATENT FORAMEN OVALE ON MEDICAL TREATMENT ALONE: POPULATION[1]BASED STUDY AND SYSTEMATIC REVIEW Prognosis of Cryptogenic Stroke With Patent Foramen Ovale at Older Ages and Implications for Trials: A Population-Based Study and Systematic Review | Congenital Defects | JAMA Neurology | JAMA Network
- Mark Bakker: GENOME-WIDE ASSOCIATION STUDY OF INTRACRANIAL ANEURYSMS REVEALS 17 RISK LOCI, POLYGENIC ARCHITECTURE, GENETIC OVERLAP WITH CLINICAL RISK FACTORS, AND OPPORTUNITIES FOR TREATMENT Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors | Nature Genetics
- Laura Ibanez: GENETIC INFLUENCES ON EARLY NEUROLOGICAL INSTABILITY AFTER ACUTE ISCHEMIC STROKE: GENISIS RESULTS Overlap in the Genetic Architecture of Stroke Risk, Early Neurological Changes, and Cardiovascular Risk Factors | Stroke (ahajournals.org)
- David Werring: NOVEL MRI-BASED RISK SCORES FOR INTRACRANIAL HAEMORRHAGE AND ISCHAEMIC STROKE IN PATIENTS TAKING ANTITHROMBOTIC THERAPY: A POOLED ANALYSIS FROM THE MICROBLEEDS INTERNATIONAL COLLABORATIVE NETWORK Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies – ScienceDirect
- Craig Anderson: LOWERING BLOOD PRESSURE AFTER ACUTE INTRACEREBRAL HAEMORRHAGE: AN IPD SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED TRIALS IN THE BLOOD PRESSURE IN ACUTE STROKE COLLABORATION (BASC) Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data | Journal of Neurology, Neurosurgery & Psychiatry (bmj.com)
- Götz Thomalla: THROMBOLYSIS IN UNKNOWN ONSET STROKE GUIDED BYADVANCED IMAGING – INDIVIDUAL PATIENT DATA META-ANALYSIS FROM WAKE-UP, THAWS, EXTEND, ECASS-4, AND MR WITNESS Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data – ScienceDirect
- Karl Haeusler: SYSTEMATIC MONITORING FOR DETECTION OF ATRIAL FIBRILLATION IN PATIENTS WITH ACUTE ISCHEMIC STROKE – A PROSPECTIVE RANDOMIZED MULTICENTER STUDY Systematic monitoring for detection of atrial fibrillation in patients with acute ischaemic stroke (MonDAFIS): a randomised, open-label, multicentre study – ScienceDirect
- Sreeja Kodali: MULTI-TRAJECTORY MODELING OF BLOOD PRESSURE AFTER THROMBECTOMY: A MULTICENTER ANALYSIS OF INDIVIDUAL PATIENT BLOOD PRESSURE DATA Blood Pressure Trajectory Groups and Outcome After Endovascular Thrombectomy: A Multicenter Study | Stroke (ahajournals.org)
- Noor Samuels: HIGH SYSTOLIC BLOOD PRESSURE AFTER ENDOVASCULAR TREATMENT FOR ISCHEMIC STROKE IS ASSOCIATED WITH WORSE OUTCOME: RESULTS FROM THE MR CLEAN REGISTRY Blood Pressure in the First 6 Hours Following Endovascular Treatment for Ischemic Stroke Is Associated With Outcome | Stroke (ahajournals.org)
- Mikael Mazighi: BLOOD PRESSURE TARGET IN ACUTE STROKE TO REDUCE HEMORRHAGE AFTER ENDOVASCULAR THERAPY: THE RANDOMIZED BP TARGET STUDY Frontiers | Blood Pressure Target in Acute Stroke to Reduce HemorrhaGe After Endovascular Therapy: The Randomized BP TARGET Study Protocol (frontiersin.org)
- Rob van de Graaf: EFFECT OF MODERATE DOSE UNFRACTIONATED HEPARIN DURING ENDOVASCULAR TREATMENT: INTERIM RESULTS OF A MULTICENTER RANDOMIZED CLINICAL TRIAL. MR CLEAN-MED Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial – The Lancet
