The European Stroke Organisation (ESO) Guidelines on Intravenous Thrombolysis (IVT) for Acute Ischaemic Stroke

This video interview was conducted with help from ESO’s valued media partner Oruen.

Guidelines in Development

  • Brain oedema management in acute Stroke
  • Carotid Stenosis
  • Dissection
  • Management of unruptured aneurysm
  • Management of hypertension in acute ischemic stroke and intracerebral hemorrhage
  • Secondary Prevention non-related to AF
  • Small Vessel Disease
  • Stroke & Dysphagia
  • TIA Management
  • PFO Treatment
  • Women & Stroke

ESO publishes two 
types of documents

  1. Full ESO Guideline Document with evidence-based 
recommendations and expert consensus statements 
(see criteria for the ECS in the table)
  2. Expedited recommendation in case at least one 
guideline-changing RCT is published


Evidence-based recommendation

  • GRADE methodology and ESO Guideline SOP
  • High-quality outcome
  • Comprehensive (detailed document available online)
  • Time-consuming process
  • Published in the ESJ

Expert Consensus Statement (ECS)

  • Only when not enough evidence to provide an evidence-based recommendation
  • Presented in the guideline document with the result of a majority vote


  • When at least one guideline-changing RCT is published
  • One main PICO question to be answered
  • Based on GRADE except that a formal systematic review is not mandatory
  • Quickly available on the ESO website / MAGICApp
  • Published in the ESJ