Important studies presented at ESOC 2019
- Hugues Chabriat: RESTORE BRAIN STUDY: A RANDOMIZED EFFICACY AND SAFETY TRIAL WITH ORAL S 44819 AFTER RECENT ISCHEMIC STROKE EVENT Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke
- Fernando Picco: THE RESCUE BRAIN TRIAL: A FRENCH MULTICENTER RANDOMIZED TRIAL ON NEUROPROTECTION WITH LOWER LIMB ISCHEMIC PER-CONDITIONING IN THE ACUTE PHASE OF CEREBRAL INFARCTION RESCUE BRAIN Randomized Clinical Trial – JAMA Neurology
- Masatoshi Koga: MRI-GUIDED THROMBOLYSIS WITH ALTEPLASE AT 0.6MG/KG FOR STROKE WITH UNKNOWN TIME OF ONSET: THAWS RANDOMIZED CONTROLLED TRIAL Thrombolysis With Alteplase at 0.6 mg/kg for Stroke With Unknown Time of Onset | Stroke (ahajournals.org)
- Christopher Price: PARAMEDIC ACUTE STROKE TREATMENT ASSESSMENT (PASTA) TRIAL: MAIN RESULTS PASTA trial – Jama Neurology
- Vivian Fu: TAKING CHARGE AFTER STROKE: A RANDOMISED CONTROLLED TRIAL OF A PERSON-CENTRED, SELF-DIRECTED, REHABILITATION INTERVENTION IN COMMUNITY STROKE SURVIVORS Taking Charge after Stroke: A randomized controlled trial – Int J Stroke
- Helen Rodgers: ROBOT ASSISTED TRAINING FOR THE UPPER LIMB AFTER STROKE (RATULS): MAIN RESULTS RATULS trial – The Lancet
- Bertrand Lapergue: COMBINED USE OF CONTACT ASPIRATION AND THE STENT RETRIEVER TECHNIQUE VERSUS STENT RETRIEVER ALONE FOR RECANALIZATION IN ACUTE CEREBRAL INFARCTION: THE RANDOMIZED ASTER2 TRIAL Effect of Thrombectomy With Combined Contact Aspiration and Stent Retriever vs Stent Retriever Alone on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion: The ASTER2 Randomized Clinical Trial | Cerebrovascular Disease | JAMA | JAMA Network
- Henry Ma: EXTENDING THROMBOLYSIS TO 9 HOURS AND WAKE-UP STROKE USING PERFUSION IMAGING: A META-ANALYSIS OF INDIVIDUAL PATIENT DATA FROM EXTEND, ECASS4-EXTEND AND EPITHET – Extending thrombolysis to 4·5-9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis – The Lancet
- Deborah Levine: BLOOD PRESSURE OVER THE LIFE COURSE AND LATER-LIFE COGNITION IN BLACKS, HISPANICS, AND WHITES (BP-COG): POOLED COHORT ANALYSIS OF ARIC, CARDIA, CHS, FOS, AND NOMAS Association Between Blood Pressure and Later-Life Cognition Among Black and White Individuals | Cardiology | JAMA Neurology | JAMA Network
- Sheila Martins: RANDOMIZATION OF ENDOVASCULAR TREATMENT WITH STENT-RETRIEVER AND/OR THROMBOASPIRATION VS. BEST MEDICAL THERAPY IN ACUTE ISCHEMIC STROKE DUE TO LARGE VESSEL OCCLUSION TRIAL (RESILIENT): FINAL RESULTS – RESILIENT trial – Int J Stroke
- Rustam al-Shahi Salman: EFFECTS OF ANTIPLATELET THERAPY AFTER STROKE DUE TO INTRACEREBRAL HAEMORRHAGE: MAIN RESULTS OF THE RESTART OR STOP ANTITHROMBOTICS RANDOMISED TRIAL (RESTART) – RESTART trial – The Lancet
- Xia Wang: THE ENHANCED CONTROL OF HYPERTENSION AND THROMBOLYSIS STROKE STUDY (ENCHANTED): THE INTERACTION BETWEEN ALTEPLASE DOSE AND BLOOD PRESSURE LOWERING TREATMENT – ENCHANTED trial – Cerebrovasc Dis
- Tom Moullaali: INTERACT2/ATACH-II IPD POOLING PROJECT TO DEFINE OPTIMAL LEVELS OF SYSTOLIC BLOOD PRESSURE CONTROL IN ACUTE INTRACEREBRAL HEMORRHAGE – Blood pressure control and clinical outcomes in acute intracerebral haemorrhage – The Lancet Neurology
- Nikola Sprigg: THE TRANEXAMIC ACID FOR INTRACEREBRAL HAEMORRHAGE-2 (TICH-2) TRIAL: RESULTS OF ONE YEAR FOLLOW UP DATA – Outcomes of TICH-2 – JAHA
- David Werring: CEREBRAL MICROBLEEDS AND FUTURE STROKE RISK AFTER ISCHAEMIC STROKE OR TRANSIENT ISCHAEMIC ATTACK: POOLED ANALYSIS OF INDIVIDUAL PATIENT DATA FROM COHORT STUDIES Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack – Lancet Neurology
- Mukul Sharma: EFFECTS OF RIVAROXABAN VS ASPIRIN ON THE OCCURRENCE OF CLINICAL AND MRI-DEFINED INFARCTS AND MICROBLEEDS IN NAVIGATE ESUS – RESULTS OF NAVIGATE MIND MRI SUBSTUDY – NAVIGATE MIND MRI Study – Int J Stroke
- Mukul Sharma: RESULTS OF THE CARDIOVASCULAR OUTCOMES FOR PEOPLE USING ANTICOAGULATION STRATEGIES (COMPASS) RANDOMIZED TRIAL MRI AND NEUROCOGNITIVE DETERIORATION SUBSTUDY (COMPASS MIND) – COMPASS MRI Study – Stroke
- Jeffrey Saver: An injectable implant to stimulate the sphenopalatine ganglion for treatment of acute ischaemic stroke up to 24 h from onset (ImpACT-24B): an international, randomised, double-blind, sham-controlled, pivotal trial – ImpACT-24B Trial – The Lancet
- Keun-Sik Hong: CILOSTAZOL VS ASPIRIN IN ISCHEMIC STROKE WITH CEREBRAL MICROBLEEDS VS PRIOR INTRACEREBRAL HEMORRHAGE: SUBGROUP ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL Cilostazol versus aspirin in ischemic stroke with cerebral microbleeds versus prior intracerebral hemorrhage – Int J Stroke
- Guillaume Turc: DISENTANGLING THE INFLUENCE OF ATRIAL SEPTAL ANEURYSM AND SHUNT SIZE ON THE RISK OF RECURRENT STROKE ASSOCIATED WITH PATENT FORAMEN OVALE Atrial Septal Aneurysm, Shunt Size, and Recurrent Stroke Risk in Patients With Patent Foramen Ovale – JACC
- Heinrich Audebert: EFFECTS OF A MULTICOMPONENT SUPPORT PROGRAM FOR INTENSIFIED SECONDARY PREVENTION IN PATIENTS WITH TRANSIENT ISCHEMIC ATTACK AND MINOR STROKE THE INSPIRE-TMS TRIAL A support programme for secondary prevention in patients with transient ischaemic attack and minor stroke (INSPiRE-TMS): an open-label, randomised controlled trial – ScienceDirect
- Peter Willeit: STROKE-CARD CARE TO PREVENT CARDIOVASCULAR EVENTS AND IMPROVE QUALITY OF LIFE AFTER ACUTE ISCHAEMIC STROKE OR TIA: A RANDOMISED CLINICAL TRIAL STROKE-CARD care to prevent cardiovascular events and improve quality of life after acute ischaemic stroke or TIA: A randomised clinical trial – ScienceDirect
- Emma Patchwood: ORGANISING SUPPORT FOR CARERS OF STROKE SURVIVORS (OSCARSS): FIRST RELEASE OF FINDINGS FROM A CLUSTER RANDOMISED CONTROLLED TRIAL Organising Support for Carers of Stroke Survivors (OSCARSS): a cluster randomised controlled trial with economic evaluation | BMJ Open