Important studies presented at ESOC 2015
Three new positive endovascular trials
- Antoni Davalos: REVASCAT: RANDOMIZED TRIAL OF REVASCULARIZATION WITH SOLITAIRE® DEVICE VERSUS BEST MEDICAL THERAPY IN THE TREATMENT OF ACUTE STROKE DUE TO ANTERIOR CIRCULATION LARGE VESSEL OCCLUSION-> Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke | NEJM
- Jay Mocco: RESULTS OF THE THERAPY TRIAL: A PROSPECTIVE, RANDOMIZED TRIAL TO DEFINE THE ROLE OF MECHANICAL THROMBECTOMY AS ADJUNCTIVE TREATMENT TO IV RTPA IN ACUTE ISCHEMIC STROKE Aspiration Thrombectomy After Intravenous Alteplase Versus Intravenous Alteplase Alone | Stroke (ahajournals.org)
- Serge Bracard: THRACE STUDY: INTERMEDIATE ANALYSIS RESULTS Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial – ScienceDirect
Sub-analysis of positive endovascular trials that were presented at WSC and ISC:
- Michael Hill: ENDOVASCULAR TREATMENT FOR SMALL CORE AND ANTERIOR CIRCULATION PROXIMAL OCCLUSION WITH EMPHASIS ON MINIMIZING CT TO RECANALIZATION TIMES (ESCAPE) original publication: Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke | NEJM
- Olvert Berkhemer: THE EFFECT OF BASELINE STROKE SEVERITY ON TREATMENT EFFECT IN THE MR CLEAN TRIAL. original publication: A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke | NEJM
- Mayank Goyal: ENTRY IMAGING VESSEL AND PARENCHYMAL FINDINGS CORRELATED WITH CLINICAL OUTCOME IN THE SWIFT PRIME TRIAL original publication: Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke | NEJM
- The Extend-IA trial: original publication: Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection | NEJM
Another important study:
- Hugh Markus: THE CERVICAL ARTERY DISSECTION IN STROKE STUDY (CADISS) – ONE YEAR FOLLOW-UP RESULTS original publication: Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial – ScienceDirect
