Who Watches the Watchmen? – LAA closure for stroke protection

As primary source of thromboembolism in atrial fibrillation, the left atrial appendage (LAA) qualifies as a target for mechanical interventions for stroke prevention.1 In particular for patients at high bleeding risk, local therapies, which exclude the LAA from the systemic circulation, offer a treatment alternative to oral anticoagulation for cardioembolic stroke prevention.