by Davide Strambo
A walk around the poster during the morning coffee break is another good opportunity to discover something new offered by ESOC 2018. The sector of Rehabilitation Clinical Trials is filled with many novel approaches to boost recovery after stroke, as computer Based Cognitive Rehabilitation (CBCR) for visuospatial disturbances (K. Svaerke et al.), transcranial random noise stimulation for upper limb function recovery (V. Arnao et al.) and an hybrid assistive limb exoskeleton to improve gait (A. Wall et al.). If you like innovation and high-tech, keep walking to the sections of Small Vessels Disease and Cognition and Vascular Cognitive Impairment, where studies conducted with advanced MRI techniques provides new interesting perspectives on these topics still largely undiscovered (NOVEL DTI MARKER IS ASSOCIATED WITH PROCESSING SPEED DEFICITS IN SMALL VESSEL DISEASE WITHOUT APPARENT CLINICAL SYMPTOMS –B. Lam et al.; APATHY IS ASSOCIATED WITH DISRUPTION TO DISTINCT, LARGE-SCALE WHITE MATTER NETWORKS –J. Tay et al.; and WHITE MATTER INTEGRITY USING DIFFUSION TENSOR IMAGING FOLLOWING TRANSIENT ISCHEMIC ATTACK – S. Tariq et al.). You will also read interesting data on microbleeds as you look for HETEROGENEOUS ORIGIN AND EVOLUTION OF MICROBLEEDS IN CEREBRAL SMALL VESSEL DISEASE (K. Wiegertjes), a study showing that microbleeds of similar appearance on MRI can originate both from hemorrhage and ischemic infarct. Together with neuroimaging, also blood biomarkers show a promising role in the field of small vessel disease, as we can see in SERUM NEUROFILAMENT LIGHT CHAIN PREDICTS PROGRESSIVE MICROSTRUCTURAL DAMAGE AND PSYCHOMOTOR SPEED DECLINE IN CEREBRAL SMALL VESSEL DISEASE (N. Peters et al.).
To keep the contact with you clinical neurology skills, check out this study refining the tools for the bedside diagnosis of cognitive impairment after stroke: THE QUEEN SQUARE COGNITIVE ASSESSMENT FOR STROKE (QS-CAS): IMPROVING ON THE MONTREAL COGNITIVE ASSESSMENT (MOCA) (E. Chan et al).
Before the end of the coffee-break pay a visit to the section Imaging – Hyperacute: yesterday we heard how FLAIR-DWI mismatch can be effectively used to select wake-up stroke patients eligible to IV thrombolysis: here Damion et al. show us that stroke onset estimation can be further refined with a multiparametric approach (MULTIPARAMETRIC APPROACH TO STROKE ONSET TIME ESTIMATION USING QUANTITATIVE MRI AND CLINICAL DATA). For the lovers of rare pearls two studies by T. Thirugnanachandran et al. provide a detailed clinic-radiological characterisation of anterior cerebral artery strokes (A DIGITAL MAP OF THE ANTERIOR CEREBRAL ARTERY TERRITORY ASSOCIATED WITH ANTERIOR CEREBRAL ARTERY OCCLUSION and CORTICOFUGAL FIBRE INVOLVEMENT AND MOTOR OUTCOME IN ANTERIOR CEREBRAL ARTERY STROKE).